Benzenamine, 5-fluoro-2-(2-phenylethoxy)-
5-Fluoro-2-(phenethyloxy)aniline
CAS: 946716-72-9
Molecular Formula: C14H14FNO
Benzenamine, 5-fluoro-2-(2-phenylethoxy)- - Names and Identifiers
| Name | 5-Fluoro-2-(phenethyloxy)aniline |
| Synonyms | 5-Fluoro-2-(phenethyloxy)aniline 5-FLUORO-2-(PHENETHYLOXY)ANILINE Benzenamine, 5-fluoro-2-(2-phenylethoxy)- |
| CAS | 946716-72-9 |
Benzenamine, 5-fluoro-2-(2-phenylethoxy)- - Physico-chemical Properties
| Molecular Formula | C14H14FNO |
| Molar Mass | 231.27 |
| Density | 1.173±0.06 g/cm3(Predicted) |
| Boling Point | 390.2±32.0 °C(Predicted) |
| pKa | 3.72±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD08687877 |
Benzenamine, 5-fluoro-2-(2-phenylethoxy)- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
Benzenamine, 5-fluoro-2-(2-phenylethoxy)- - Introduction
5-fluoro-2-(phenylethoxy) aniline is an organic compound with the chemical structure of C14H14FNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: A colorless to pale yellow crystalline solid.
-Melting point: about 30-34 degrees Celsius.
-Boiling point: about 342-346 degrees Celsius.
-Solubility: The compound is soluble in most organic solvents.
Use:
-5-Fluoro-2-(phenylethoxy) aniline is often used as an intermediate in organic synthesis for the preparation of other organic compounds.
-The application of this compound in the field of medicine needs to be studied.
Preparation Method:
-5-fluoro-2-(phenylethoxy) aniline can be synthesized by the reaction of phenethylamine with 5-fluoro-2-nitrophenol. Under the reaction conditions, phenethylamine is first reacted with diethyl iodophosphate to obtain p-nitrophenethylamine. Next, p-nitrophenethylamine is reacted with 5-fluoro-2-hydroxybenzaldehyde to give 5-fluoro-2-(phenethoxy) aniline.
Safety Information:
-5-fluoro-2-(phenylethoxy) aniline is generally stable, but it still needs to be stored and handled under appropriate conditions.
-Use appropriate personal protective equipment, such as chemical protective gloves and goggles.
-Avoid contact with skin, eyes and inhalation of dust or vapours.
-In case of accidental contact, rinse immediately with plenty of water and seek medical advice and treatment.
-Detailed safety information and operating instructions can be found in the safety data sheet of the compound.
Nature:
-Appearance: A colorless to pale yellow crystalline solid.
-Melting point: about 30-34 degrees Celsius.
-Boiling point: about 342-346 degrees Celsius.
-Solubility: The compound is soluble in most organic solvents.
Use:
-5-Fluoro-2-(phenylethoxy) aniline is often used as an intermediate in organic synthesis for the preparation of other organic compounds.
-The application of this compound in the field of medicine needs to be studied.
Preparation Method:
-5-fluoro-2-(phenylethoxy) aniline can be synthesized by the reaction of phenethylamine with 5-fluoro-2-nitrophenol. Under the reaction conditions, phenethylamine is first reacted with diethyl iodophosphate to obtain p-nitrophenethylamine. Next, p-nitrophenethylamine is reacted with 5-fluoro-2-hydroxybenzaldehyde to give 5-fluoro-2-(phenethoxy) aniline.
Safety Information:
-5-fluoro-2-(phenylethoxy) aniline is generally stable, but it still needs to be stored and handled under appropriate conditions.
-Use appropriate personal protective equipment, such as chemical protective gloves and goggles.
-Avoid contact with skin, eyes and inhalation of dust or vapours.
-In case of accidental contact, rinse immediately with plenty of water and seek medical advice and treatment.
-Detailed safety information and operating instructions can be found in the safety data sheet of the compound.
Last Update：2024-04-09 02:00:57
